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| 29/03/2022 | 18:30 | Rot-Weiss Essen | - | SpVg Schonnebeck | 3:0 (1:0) | |
| 30/03/2022 | 18:30 | Schwarz-Weiß Essen | - | SV 19 Straelen | 1:2 | |
| 06/04/2022 | 18:30 | 1. FC Bocholt | - | MSV Duisburg | 0:2 | |
| 18:30 | FC Kray | - | Wuppertaler SV | 2:3 |
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| 29/03/2022 | 18:30 | Rot-Weiss Essen | - | SpVg Schonnebeck | 3:0 (1:0) | |
| 30/03/2022 | 18:30 | Schwarz-Weiß Essen | - | SV 19 Straelen | 1:2 | |
| 06/04/2022 | 18:30 | 1. FC Bocholt | - | MSV Duisburg | 0:2 | |
| 18:30 | FC Kray | - | Wuppertaler SV | 2:3 |
