 |
 |
| Quarter-finals | ||||||
|---|---|---|---|---|---|---|
| 24/04/2021 | 21:30 | América de Cali | - | Millonarios | 1:2 (0:1) | |
| 25/04/2021 | 21:30 | Atlético Junior | - | Santa Fe | 3:1 (1:0) | |
| 23:40 | Deportes Tolima | - | Deportivo Cali | 3:0 (1:0) | ||
| 26/04/2021 | 02:00 | La Equidad | - | Atlético Nacional | 1:0 (0:0) | |
| 02/05/2021 | 00:00 | Millonarios | - | América de Cali | 0:0 (0:0) | |
| 19:00 | Santa Fe | - | Atlético Junior | 0:0 (0:0) | ||
| 21:30 | Atlético Nacional | - | La Equidad | 2:2 (0:0) | ||
| 04/06/2021 | 21:30 | Deportivo Cali | - | Deportes Tolima | 2:0 (2:0) | |
| Semi-finals | ||||||
| 10/06/2021 | 22:00 | Atlético Junior | - | Millonarios | 3:2 (3:1) | |
| 11/06/2021 | 00:05 | Deportes Tolima | - | La Equidad | 1:1 (1:1) | |
| 13/06/2021 | 19:30 | Millonarios | - | Atlético Junior | 2:0 (2:0) | |
| 15/06/2021 | 01:00 | La Equidad | - | Deportes Tolima | 1:2 (0:1) | |
| Final | ||||||
| 18/06/2021 | 02:00 | Deportes Tolima | - | Millonarios | 1:1 (1:0) | |
| 20/06/2021 | 21:00 | Millonarios | - | Deportes Tolima | 1:2 (1:0) | |
