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| 1st(1st leg) | Deportivo Guadalajara | - | Deportivo Toluca | 1:0 (0:0) | ||
| 2nd (2nd leg) | Deportivo Toluca | - | Deportivo Guadalajara | 0:0 (0:0) | ||
| 1st(1st leg): 09/05/2024 02:05 | 2nd (2nd leg): 12/05/2024 03:10 | Winner: Deportivo Guadalajara | ||||
| 1st(1st leg) | CF Pachuca | - | CF América | 1:1 (1:1) | ||
| 2nd (2nd leg) | CF América | - | CF Pachuca | 1:1 (0:1) | ||
| 1st(1st leg): 09/05/2024 04:16 | 2nd (2nd leg): 12/05/2024 01:00 | |||||
| 1st(1st leg) | Pumas UNAM | - | Cruz Azul | 0:2 (0:1) | ||
| 2nd (2nd leg) | Cruz Azul | - | Pumas UNAM | 2:2 (0:0) | ||
| 1st(1st leg): 10/05/2024 02:00 | 2nd (2nd leg): 13/05/2024 02:00 | Winner: Cruz Azul | ||||
| 1st(1st leg) | UANL Tigres | - | CF Monterrey | 1:2 (1:1) | ||
| 2nd (2nd leg) | CF Monterrey | - | UANL Tigres | 1:1 (0:1) | ||
| 1st(1st leg): 10/05/2024 04:10 | 2nd (2nd leg): 13/05/2024 04:10 | Winner: CF Monterrey | ||||
