Premier League   M. W D L goals
  at home 20 11 5 4 31 : 18
  Away 20 5 7 8 29 : 33
  40 16 12 12 60 : 51
Championship   M. W D L goals
  at home 17 10 1 6 27 : 18
  Away 17 4 2 11 18 : 33
  34 14 3 17 45 : 51
FA Cup   M. W D L goals
  Away 1 0 0 1 0 : 1
  1 0 0 1 0 : 1
League Cup   M. W D L goals
  at home 1 1 0 0 3 : 2
  Away 1 1 0 0 3 : 2
  2 2 0 0 6 : 4
overall   M. W D L goals
  at home 38 22 6 10 61 : 38
  Away 39 10 9 20 50 : 69
  Neutral Place 0 0 0 0 0 : 0
  77 32 15 30 111 : 107
Premier League
2017/2018 29. Round Southampton FC - Stoke City 0:0 (0:0)
2017/2018 7. Round Stoke City - Southampton FC 2:1 (1:0)
2016/2017 38. Round Southampton FC - Stoke City 0:1 (0:0)
2016/2017 16. Round Stoke City - Southampton FC 0:0 (0:0)
2015/2016 30. Round Stoke City - Southampton FC 1:2 (0:2)
2015/2016 13. Round Southampton FC - Stoke City 0:1 (0:1)
2014/2015 33. Round Stoke City - Southampton FC 2:1 (0:1)
2014/2015 9. Round Southampton FC - Stoke City 1:0 (1:0)
2013/2014 25. Round Southampton FC - Stoke City 2:2 (2:2)
2013/2014 10. Round Stoke City - Southampton FC 1:1 (1:1)
2012/2013 38. Round Southampton FC - Stoke City 1:1 (0:0)
2012/2013 20. Round Stoke City - Southampton FC 3:3 (1:3)
1984/1985 32. Round Southampton FC - Stoke City 0:0 (0:0)
1984/1985 10. Round Stoke City - Southampton FC 1:3 (1:2)
1983/1984 40. Round Stoke City - Southampton FC 1:1 (0:0)
1983/1984 16. Round Southampton FC - Stoke City 3:1 (2:1)
1982/1983 38. Round Stoke City - Southampton FC 1:1 (0:0)
1982/1983 17. Round Southampton FC - Stoke City 1:0 (0:0)
1981/1982 33. Round Southampton FC - Stoke City 4:3 (3:0)
1981/1982 13. Round Stoke City - Southampton FC 0:2 (0:1)
1980/1981 34. Round Stoke City - Southampton FC 1:2 (0:1)
1980/1981 11. Round Southampton FC - Stoke City 1:2 (1:0)
1979/1980 39. Round Stoke City - Southampton FC 1:2 (1:0)
1979/1980 18. Round Southampton FC - Stoke City 3:1 (1:0)
1973/1974 34. Round Stoke City - Southampton FC 4:1 (1:1)
1973/1974 12. Round Southampton FC - Stoke City 3:0 (3:0)
1972/1973 17. Round Stoke City - Southampton FC 3:3 (2:2)
1972/1973 2. Round Southampton FC - Stoke City 1:0 (1:0)
1971/1972 26. Round Stoke City - Southampton FC 3:1 (1:0)
1971/1972 2. Round Southampton FC - Stoke City 3:1 (2:0)
1970/1971 26. Round Southampton FC - Stoke City 2:1 (1:1)
1970/1971 19. Round Stoke City - Southampton FC 0:0 (0:0)
1969/1970 27. Round Southampton FC - Stoke City 0:0 (0:0)
1969/1970 7. Round Stoke City - Southampton FC 2:1 (0:0)
1968/1969 13. Round Stoke City - Southampton FC 1:0 (0:0)
1968/1969 6. Round Southampton FC - Stoke City 2:0 (0:0)
1967/1968 28. Round Southampton FC - Stoke City 1:2 (0:0)
1967/1968 9. Round Stoke City - Southampton FC 3:2 (0:0)
1966/1967 15. Round Southampton FC - Stoke City 3:2 (0:0)
1966/1967 12. Round Stoke City - Southampton FC 3:2 (0:0)
Championship
2023/2024 45. Round Southampton FC - Stoke City 0:1 (0:1)
2023/2024 10. Round Stoke City - Southampton FC 0:1 (0:1)
2007/2008 32. Round Stoke City - Southampton FC 3:2 (3:0)
2007/2008 3. Round Southampton FC - Stoke City 3:2 (1:1)
2006/2007 37. Round Stoke City - Southampton FC 2:1 (1:1)
2006/2007 13. Round Southampton FC - Stoke City 1:0 (0:0)
2005/2006 43. Round Stoke City - Southampton FC 1:2 (0:2)
2005/2006 16. Round Southampton FC - Stoke City 2:0 (1:0)
1977/1978 5. Round Southampton FC - Stoke City 1:0
1977/1978 1. Round Stoke City - Southampton FC 1:0
1962/1963 9. Round Southampton FC - Stoke City 2:0
1962/1963 2. Round Stoke City - Southampton FC 3:1
1961/1962 9. Round Southampton FC - Stoke City 5:1
1961/1962 5. Round Stoke City - Southampton FC 3:2
1960/1961 9. Round Southampton FC - Stoke City 0:1
1960/1961 4. Round Stoke City - Southampton FC 1:2
1932/1933 8. Round Stoke City - Southampton FC 3:1
1932/1933 4. Round Southampton FC - Stoke City 1:0
1931/1932 6. Round Stoke City - Southampton FC 2:0
1931/1932 2. Round Southampton FC - Stoke City 1:2
1930/1931 7. Round Stoke City - Southampton FC 1:3
1930/1931 3. Round Southampton FC - Stoke City 2:1
1929/1930 7. Round Southampton FC - Stoke City 2:1
1929/1930 3. Round Stoke City - Southampton FC 4:0
1928/1929 9. Round Stoke City - Southampton FC 3:0
1928/1929 5. Round Southampton FC - Stoke City 0:0
1927/1928 5. Round Stoke City - Southampton FC 2:1
1927/1928 1. Round Southampton FC - Stoke City 3:6
1925/1926 10. Round Stoke City - Southampton FC 1:1
1925/1926 5. Round Southampton FC - Stoke City 1:2
1924/1925 2. Round Southampton FC - Stoke City 3:0
1924/1925 2. Round Stoke City - Southampton FC 2:0
1923/1924 3. Round Southampton FC - Stoke City 0:1
1923/1924 2. Round Stoke City - Southampton FC 1:1
FA Cup
1932/1933 3. Round Stoke City - Southampton FC 1:0
League Cup
2024/2025 Round of 16 Southampton FC - Stoke City 3:2 (2:1)
2014/2015 Round of 16 Stoke City - Southampton FC 2:3 (0:2)

For games that were decided on penalties the score after 120 minutes will be included in the ranking