Copa Libertadores   M. W D L goals
  at home 4 1 2 1 4 : 3
  Away 2 2 0 0 8 : 4
  6 3 2 1 12 : 7
Primera División   M. W D L goals
  at home 24 11 4 9 34 : 26
  Away 25 8 11 6 32 : 30
  Neutral Place 3 2 1 0 4 : 1
  52 21 16 15 70 : 57
overall   M. W D L goals
  at home 28 12 6 10 38 : 29
  Away 27 10 11 6 40 : 34
  Neutral Place 3 2 1 0 4 : 1
  58 24 18 16 82 : 64
Copa Libertadores
1996 Group 2 Peñarol - Defensor Sporting 1:1 (0:0)
1996 Group 2 Defensor Sporting - Peñarol 2:4 (2:2)
1982 Group 2 Peñarol - Defensor Sporting 0:0 (0:0)
1982 Group 2 Peñarol - Defensor Sporting 3:0 (1:0)
1977 Group 1 Defensor Sporting - Peñarol 2:4 (2:3)
1977 Group 1 Peñarol - Defensor Sporting 0:2 (0:0)
Primera División
2024 Clausura 13. Round Peñarol - Defensor Sporting 2:0 (1:0)
2024 Intermedio Group A Peñarol - Defensor Sporting 1:0 (0:0)
2024 Apertura 13. Round Defensor Sporting - Peñarol 0:2 (0:1)
2023 Clausura 4. Round Peñarol - Defensor Sporting 2:1 (1:1)
2023 Intermedio Group A Peñarol - Defensor Sporting 2:1 (0:0)
2023 Apertura 4. Round Defensor Sporting - Peñarol 2:2 (1:1)
2022 Clausura 2. Round Defensor Sporting - Peñarol 2:3 (0:1)
2022 Apertura 2. Round Peñarol - Defensor Sporting 0:1 (0:1)
2020 Clausura 2. Round Peñarol - Defensor Sporting 1:2 (0:0)
2020 Intermedio Group B Defensor Sporting - Peñarol 2:1 (2:0)
2020 Apertura 2. Round Defensor Sporting - Peñarol 2:1 (0:0)
2019 Clausura 1. Round Peñarol - Defensor Sporting 1:0 (1:0)
2019 Intermedio 4. Round Defensor Sporting - Peñarol 2:2 (0:1)
2019 Apertura 1. Round Defensor Sporting - Peñarol 0:1 (0:0)
2018 Clausura 15. Round Defensor Sporting - Peñarol 1:2 (1:0)
2018 Intermedio 7. Round Defensor Sporting - Peñarol 1:3 (0:1)
2018 Apertura 15. Round Peñarol - Defensor Sporting 4:1 (1:1)
2017 Playoff Final Peñarol - Defensor Sporting 4:2 (0:0, 0:0, 0:0) pso
2017 Playoff 1. Round Defensor Sporting - Peñarol 0:1 (0:0)
2017 Clausura 8. Round Peñarol - Defensor Sporting 3:1 (1:1)
2017 Intermedio 7. Round Peñarol - Defensor Sporting 2:3 (1:2)
2017 Apertura 8. Round Defensor Sporting - Peñarol 2:2 (2:1)
2016 15. Round Peñarol - Defensor Sporting 0:2 (0:1)
2015/2016 Clausura 3. Round Peñarol - Defensor Sporting 5:1 (2:1)
2015/2016 Apertura 3. Round Defensor Sporting - Peñarol 3:1 (1:1)
2014/2015 Clausura 4. Round Peñarol - Defensor Sporting 2:0 (1:0)
2014/2015 Apertura 4. Round Defensor Sporting - Peñarol 0:0 (0:0)
2013/2014 Clausura 2. Round Peñarol - Defensor Sporting 2:2 (1:1)
2013/2014 Apertura 2. Round Defensor Sporting - Peñarol 1:1 (0:0)
2012/2013 Playoff Final Defensor Sporting - Peñarol 1:3 (0:2)
2012/2013 Clausura 10. Round Defensor Sporting - Peñarol 1:0 (1:0)
2012/2013 Apertura 10. Round Peñarol - Defensor Sporting 2:1 (1:0)
2011/2012 Clausura 4. Round Defensor Sporting - Peñarol 0:0 (0:0)
2011/2012 Apertura 4. Round Peñarol - Defensor Sporting 1:0 (0:0)
2010/2011 Clausura 13. Round Defensor Sporting - Peñarol 1:1 (1:1)
2010/2011 Apertura 13. Round Peñarol - Defensor Sporting 0:1 (0:1)
2009/2010 Clausura 10. Round Defensor Sporting - Peñarol 2:3 (1:0)
2009/2010 Apertura 10. Round Peñarol - Defensor Sporting 1:1 (0:0)
2008/2009 Clausura 5. Round Peñarol - Defensor Sporting 0:1 (0:1)
2008/2009 Apertura 6. Round Defensor Sporting - Peñarol 0:0
2008 Liguilla 2. Round Defensor Sporting - Peñarol 3:0
2007/2008 Championship Playoff Final Defensor Sporting - Peñarol 0:0
2007/2008 Championship Playoff Final Peñarol - Defensor Sporting 1:2
2007/2008 Clausura 10. Round Defensor Sporting - Peñarol 0:1
2007/2008 Apertura 10. Round Peñarol - Defensor Sporting 0:2
2006/2007 Clausura 1. Round Defensor Sporting - Peñarol 2:2
2006/2007 Apertura 1. Round Peñarol - Defensor Sporting 0:1
2005/2006 Clausura 7. Round Peñarol - Defensor Sporting 1:1
2005/2006 Apertura 7. Round Defensor Sporting - Peñarol 1:1
2004/2005 Clausura 5. Round Peñarol - Defensor Sporting 1:1
2004/2005 Apertura 5. Round Defensor Sporting - Peñarol 2:1
2003 Clausura 1. Round Defensor Sporting - Peñarol 0:2

For games that were decided on penalties the score after 120 minutes will be included in the ranking