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| 1st(1st leg) | Zamora FC | - | Mineros de Guayana | 2:1 (1:0) | ||
| 2nd (2nd leg) | Mineros de Guayana | - | Zamora FC | 1:0 (0:0) | ||
| 1st(1st leg): 24/05/2019 23:00 | 2nd (2nd leg): 01/06/2019 21:00 | Winner: Mineros de Guayana | ||||
| 1st(1st leg) | Zulia FC | - | Caracas FC | 3:2 (0:2) | ||
| 2nd (2nd leg) | Caracas FC | - | Zulia FC | 1:2 (0:0) | ||
| 1st(1st leg): 25/05/2019 21:00 | 2nd (2nd leg): 03/06/2019 22:00 | Winner: Zulia FC | ||||
| 1st(1st leg) | Aragua FC | - | Estudiantes de Mérida | 1:2 (0:1) | ||
| 2nd (2nd leg) | Estudiantes de Mérida | - | Aragua FC | 1:1 (0:1) | ||
| 1st(1st leg): 26/05/2019 22:00 | 2nd (2nd leg): 02/06/2019 22:00 | Winner: Estudiantes de Mérida | ||||
| 1st(1st leg) | Atlético Venezuela | - | Carabobo FC | 2:2 (1:0) | ||
| 2nd (2nd leg) | Carabobo FC | - | Atlético Venezuela | 1:0 (0:0) | ||
| 1st(1st leg): 27/05/2019 21:00 | 2nd (2nd leg): 31/05/2019 21:00 | Winner: Carabobo FC | ||||
