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| 26/10/2011 | 11:00 | Stal Dniprodzerzhynsk (old) | - | Chernomorets Odessa | 0:4 (0:3) | |
| 13:00 | FK Bukovina | - | Arsenal Kiev | 0:2 (0:0) | ||
| 15:30 | Metalurh Donetsk | - | FK Krivbas (old) | 4:0 (2:0) | ||
| 16:00 | Volyn Lutsk | - | Dnipro Dnipropetrovsk | 3:2 (1:2, 2:2) aet | ||
| 17:00 | PFC Sumy | - | Zorya Lugansk | 1:3 (1:1) | ||
| 17:00 | Metalurg Zaporizhya | - | Vorskla Poltava | 3:0 (1:0) | ||
| 18:00 | Karpaty Lviv | - | Metalist Kharkiv | 1:0 (0:0) | ||
| 18:15 | Dinamo Kiev | - | Shakhtar Donetsk | 2:3 (1:2) |
