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| 1st(1st leg) | FK Zalgiris | - | CFR Cluj | 1:2 (0:1) | ||
| 2nd (2nd leg) | CFR Cluj | - | FK Zalgiris | 5:1 (2:0) | ||
| 1st(1st leg): 27/07/2005 16:30 | 2nd (2nd leg): 03/08/2005 15:00 | Winner: CFR Cluj | ||||
| 1st(1st leg) | VfL Wolfsburg | - | RC Lens | 0:0 (0:0) | ||
| 2nd (2nd leg) | RC Lens | - | VfL Wolfsburg | 4:0 (1:0) | ||
| 1st(1st leg): 27/07/2005 18:00 | 2nd (2nd leg): 03/08/2005 18:00 | Winner: RC Lens | ||||
| 1st(1st leg) | Sigma Olomouc | - | Hamburger SV | 0:1 (0:0) | ||
| 2nd (2nd leg) | Hamburger SV | - | Sigma Olomouc | 3:0 (1:0) | ||
| 1st(1st leg): 27/07/2005 19:15 | 2nd (2nd leg): 03/08/2005 19:15 | Winner: Hamburger SV | ||||
| 1st(1st leg) | Deportivo La Coruña | - | Newcastle United | 2:1 (1:0) | ||
| 2nd (2nd leg) | Newcastle United | - | Deportivo La Coruña | 1:2 (1:1) | ||
| 1st(1st leg): 27/07/2005 20:00 | 2nd (2nd leg): 03/08/2005 19:45 | Winner: Deportivo La Coruña | ||||
| 1st(1st leg) | Lazio Roma | - | Olympique Marseille | 1:1 (1:0) | ||
| 2nd (2nd leg) | Olympique Marseille | - | Lazio Roma | 3:0 (0:0) | ||
| 1st(1st leg): 27/07/2005 20:00 | 2nd (2nd leg): 03/08/2005 20:00 | Winner: Olympique Marseille | ||||
| 1st(1st leg) | Valencia CF | - | Roda JC Kerkrade | 4:0 (2:0) | ||
| 2nd (2nd leg) | Roda JC Kerkrade | - | Valencia CF | 0:0 (0:0) | ||
| 1st(1st leg): 27/07/2005 21:00 | 2nd (2nd leg): 03/08/2005 19:00 | Winner: Valencia CF | ||||
