1st(1st leg) Aston Villa - Athletic Club 2:0 (1:0)
2nd (2nd leg) Athletic Club - Aston Villa 1:1 (0:1)
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: Aston Villa
1st(1st leg) SC Bastia - Torino FC 2:1 (1:1)
2nd (2nd leg) Torino FC - SC Bastia 2:3 (1:1)
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: SC Bastia
1st(1st leg) FC Carl Zeiss Jena - Standard Liège 2:0 (1:0)
2nd (2nd leg) Standard Liège - FC Carl Zeiss Jena 1:2 (0:1)
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: FC Carl Zeiss Jena
1st(1st leg) Eintracht Frankfurt - Bayern München 4:0 (2:0)
2nd (2nd leg) Bayern München - Eintracht Frankfurt 1:2 (1:0)
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: Eintracht Frankfurt
1st(1st leg) Ipswich Town - FC Barcelona 3:0 (1:0)
2nd (2nd leg) FC Barcelona - Ipswich Town 3:1 (1:0, 3:0, 3:0) pso
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: FC Barcelona
1st(1st leg) 1. FC Magdeburg - RC Lens 4:0 (2:0)
2nd (2nd leg) RC Lens - 1. FC Magdeburg 2:0 (1:0)
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: 1. FC Magdeburg
1st(1st leg) PSV Eindhoven - Eintracht Braunschweig 2:0 (0:0)
2nd (2nd leg) Eintracht Braunschweig - PSV Eindhoven 1:2 (0:2)
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: PSV Eindhoven
1st(1st leg) Dinamo Tbilisi - Grasshopper Club Zürich 1:0 (1:0)
2nd (2nd leg) Grasshopper Club Zürich - Dinamo Tbilisi 4:0 (1:0)
1st(1st leg): 23/11/1977 2nd (2nd leg): 07/12/1977 Winner: Grasshopper Club Zürich