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| 1st(1st leg) | Gençlerbirliği | - | Bursaspor | 1:0 (1:0) | ||
| 2nd (2nd leg) | Bursaspor | - | Gençlerbirliği | 2:1 (1:1) | ||
| 1st(1st leg): 26/12/2017 15:30 | 2nd (2nd leg): 16/01/2018 13:00 | Winner: Gençlerbirliği | ||||
| 1st(1st leg) | Galatasaray | - | Bucaspor | 3:0 (3:0) | ||
| 2nd (2nd leg) | Bucaspor | - | Galatasaray | 0:3 (0:2) | ||
| 1st(1st leg): 26/12/2017 17:30 | 2nd (2nd leg): 18/01/2018 17:30 | Winner: Galatasaray | ||||
| 1st(1st leg) | Giresunspor | - | İstanbul Başakşehir | 3:1 (1:0) | ||
| 2nd (2nd leg) | İstanbul Başakşehir | - | Giresunspor | 2:1 (1:1) | ||
| 1st(1st leg): 27/12/2017 12:00 | 2nd (2nd leg): 17/01/2018 15:00 | Winner: Giresunspor | ||||
| 1st(1st leg) | Kayserispor | - | Antalyaspor | 3:1 (0:1) | ||
| 2nd (2nd leg) | Antalyaspor | - | Kayserispor | 0:2 (0:1) | ||
| 1st(1st leg): 27/12/2017 13:30 | 2nd (2nd leg): 18/01/2018 15:00 | Winner: Kayserispor | ||||
| 1st(1st leg) | Atiker Konyaspor | - | Trabzonspor | 1:0 (1:0) | ||
| 2nd (2nd leg) | Trabzonspor | - | Atiker Konyaspor | 1:1 (0:1) | ||
| 1st(1st leg): 27/12/2017 15:30 | 2nd (2nd leg): 16/01/2018 15:00 | Winner: Atiker Konyaspor | ||||
| 1st(1st leg) | Fenerbahçe | - | İstanbulspor AŞ | 2:0 (0:0) | ||
| 2nd (2nd leg) | İstanbulspor AŞ | - | Fenerbahçe | 0:1 (0:0) | ||
| 1st(1st leg): 27/12/2017 17:30 | 2nd (2nd leg): 16/01/2018 17:30 | Winner: Fenerbahçe | ||||
| 1st(1st leg) | Boluspor | - | Akhisar Belediyespor | 2:1 (0:0) | ||
| 2nd (2nd leg) | Akhisar Belediyespor | - | Boluspor | 1:0 (1:0) | ||
| 1st(1st leg): 28/12/2017 13:30 | 2nd (2nd leg): 17/01/2018 11:30 | Winner: Akhisar Belediyespor | ||||
| 1st(1st leg) | Beşiktaş | - | Osmanlıspor FK | 4:1 (2:0) | ||
| 2nd (2nd leg) | Osmanlıspor FK | - | Beşiktaş | 2:1 (0:0) | ||
| 1st(1st leg): 28/12/2017 17:30 | 2nd (2nd leg): 17/01/2018 17:30 | Winner: Beşiktaş | ||||
