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| 07/01/2022 | 19:45 | Edinburgh City FC | - | Elgin City | 2:2 (1:1) | |
| 08/01/2022 | 13:00 | Stirling Albion FC | - | Kelty Hearts | 0:3 (0:1) | |
| 15:00 | Albion Rovers | - | Stenhousemuir FC | 1:2 (1:1) | ||
| 15:00 | Cowdenbeath FC | - | Annan Athletic | 1:3 (1:2) | ||
| 15:00 | Forfar Athletic | - | Stranraer FC | 3:2 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Kelty Hearts | 20 | 15 | 3 | 2 | 42:17 | 25 | 48 |
| 2 |
|
Forfar Athletic | 20 | 11 | 5 | 4 | 38:21 | 17 | 38 |
| 3 |
|
Annan Athletic | 20 | 11 | 3 | 6 | 36:24 | 12 | 36 |
| 4 |
|
Stenhousemuir FC | 20 | 7 | 5 | 8 | 30:33 | -3 | 26 |
| 5 |
|
Edinburgh City FC | 20 | 7 | 5 | 8 | 25:31 | -6 | 26 |
| 6 |
|
Stirling Albion FC | 20 | 7 | 3 | 10 | 25:28 | -3 | 24 |
| 7 |
|
Elgin City | 20 | 6 | 6 | 8 | 21:27 | -6 | 24 |
| 8 |
|
Albion Rovers | 20 | 7 | 3 | 10 | 26:34 | -8 | 24 |
| 9 |
|
Stranraer FC | 20 | 6 | 5 | 9 | 25:32 | -7 | 23 |
| 10 |
|
Cowdenbeath FC | 20 | 2 | 4 | 14 | 12:33 | -21 | 10 |
| Promotion | |
| Playoffs | |
| Relegation |
