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| 02/10/2021 | 11:00 | FC Famalicão | - | Sporting Braga | 1:0 (1:0) | |
| 03/10/2021 | 21:00 | SL Benfica | - | Portimonense SC | 1:1 (0:0) | |
| 04/10/2021 | 11:00 | Leixões SC | - | Rio Ave FC | 0:1 (0:0) | |
| 15:00 | Belenenses SAD | - | SC Farense | 2:1 (0:1) | ||
| 09/10/2021 | 15:00 | CS Marítimo | - | GD Estoril | 0:1 (0:1) | |
| 20/10/2021 | 11:00 | Vitória Guimarães | - | FC Vizela | 1:1 (0:1) |
| » Tables | Home | Away | First round | Second round |
| 1 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sporting Braga | 6 | 4 | 1 | 1 | 8:3 | 5 | 13 |
| 2 |
|
Rio Ave FC | 5 | 4 | 1 | 0 | 5:1 | 4 | 13 |
| 3 |
|
Vitória Guimarães | 5 | 2 | 1 | 2 | 9:6 | 3 | 7 |
| 4 |
|
Leixões SC | 5 | 2 | 1 | 2 | 4:3 | 1 | 7 |
| 5 |
|
FC Famalicão | 5 | 2 | 1 | 2 | 4:5 | -1 | 7 |
| 6 |
|
FC Vizela | 5 | 0 | 2 | 3 | 3:8 | -5 | 2 |
| 7 |
|
Académica de Coimbra | 5 | 0 | 1 | 4 | 3:10 | -7 | 1 |
| 2 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GD Estoril | 5 | 4 | 1 | 0 | 9:2 | 7 | 13 |
| 2 |
|
Sporting CP | 5 | 3 | 1 | 1 | 10:6 | 4 | 10 |
| 3 |
|
CS Marítimo | 5 | 3 | 0 | 2 | 10:6 | 4 | 9 |
| 4 |
|
SL Benfica | 5 | 2 | 2 | 1 | 5:4 | 1 | 8 |
| 5 |
|
Portimonense SC | 5 | 2 | 1 | 2 | 5:8 | -3 | 7 |
| 6 |
|
Belenenses SAD | 5 | 1 | 0 | 4 | 7:14 | -7 | 3 |
| 7 |
|
SC Farense | 6 | 0 | 1 | 5 | 3:9 | -6 | 1 |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs |
