 |
 |
|
|
| 30/10/2022 | 20:00 | Guaireña FC | - | Guaraní | 1:0 (1:0) | |
| 22:30 | Club Olimpia | - | 12 de Octubre de Itauguá | 3:1 (2:1) | ||
| 31/10/2022 | 20:30 | Tacuary | - | Club Nacional | 2:1 (1:1) | |
| 23:00 | Libertad | - | Cerro Porteño | 0:0 (0:0) | ||
| 01/11/2022 | 20:30 | General Caballero DJLM | - | Resistencia SC | 1:0 (1:0) | |
| 23:00 | Sportivo Ameliano | - | Sol de América | 2:1 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Olimpia | 20 | 14 | 3 | 3 | 39:18 | 21 | 45 |
| 2 |
|
Club Nacional | 20 | 13 | 5 | 2 | 29:13 | 16 | 44 |
| 3 |
|
Cerro Porteño | 20 | 12 | 6 | 2 | 28:12 | 16 | 42 |
| 4 |
|
Libertad | 20 | 9 | 4 | 7 | 31:24 | 7 | 31 |
| 5 |
|
Tacuary | 20 | 8 | 4 | 8 | 25:23 | 2 | 28 |
| 6 |
|
Guaireña FC | 20 | 7 | 6 | 7 | 23:24 | -1 | 27 |
| 7 |
|
General Caballero DJLM | 20 | 7 | 3 | 10 | 23:26 | -3 | 24 |
| 8 |
|
Sportivo Ameliano | 20 | 7 | 2 | 11 | 23:30 | -7 | 23 |
| 9 |
|
Guaraní | 20 | 5 | 5 | 10 | 19:27 | -8 | 20 |
| 10 |
|
Sol de América | 20 | 5 | 5 | 10 | 21:31 | -10 | 20 |
| 11 |
|
Resistencia SC | 20 | 5 | 5 | 10 | 16:31 | -15 | 20 |
| 12 |
|
12 de Octubre de Itauguá | 20 | 3 | 2 | 15 | 16:34 | -18 | 11 |
| Copa Libertadores |
