 |
 |
|
|
| 18/09/2022 | 21:00 | Libertad | - | Sportivo Ameliano | 2:1 (1:1) | |
| 23:30 | Guaireña FC | - | Tacuary | 1:0 (0:0) | ||
| 19/09/2022 | 21:45 | Club Nacional | - | General Caballero DJLM | 1:0 (0:0) | |
| 20/09/2022 | 00:15 | Guaraní | - | Club Olimpia | 2:1 (0:1) | |
| 21:45 | Sol de América | - | Resistencia SC | 0:1 (0:0) | ||
| 21/09/2022 | 00:15 | 12 de Octubre de Itauguá | - | Cerro Porteño | 0:1 (0:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Nacional | 12 | 7 | 4 | 1 | 17:9 | 8 | 25 |
| 2 |
|
Cerro Porteño | 12 | 7 | 4 | 1 | 15:7 | 8 | 25 |
| 3 |
|
Libertad | 12 | 7 | 1 | 4 | 25:17 | 8 | 22 |
| 4 |
|
Club Olimpia | 12 | 6 | 3 | 3 | 21:14 | 7 | 21 |
| 5 |
|
Guaireña FC | 12 | 5 | 3 | 4 | 19:16 | 3 | 18 |
| 6 |
|
Tacuary | 12 | 5 | 2 | 5 | 12:9 | 3 | 17 |
| 7 |
|
Guaraní | 12 | 3 | 5 | 4 | 12:15 | -3 | 14 |
| 8 |
|
Resistencia SC | 12 | 3 | 5 | 4 | 9:14 | -5 | 14 |
| 9 |
|
Sol de América | 12 | 4 | 2 | 6 | 12:18 | -6 | 14 |
| 10 |
|
Sportivo Ameliano | 12 | 4 | 1 | 7 | 14:16 | -2 | 13 |
| 11 |
|
General Caballero DJLM | 12 | 3 | 2 | 7 | 12:21 | -9 | 11 |
| 12 |
|
12 de Octubre de Itauguá | 12 | 2 | 0 | 10 | 8:20 | -12 | 6 |
| Copa Libertadores |
