 |
 |
|
|
| 10/09/2022 | 00:15 | Resistencia SC | - | Cerro Porteño | 0:2 (0:1) | |
| 21:45 | Guaireña FC | - | Libertad | 4:0 (0:0) | ||
| 11/09/2022 | 00:15 | Tacuary | - | Guaraní | 2:0 (2:0) | |
| 21:00 | Sportivo Ameliano | - | Club Nacional | 1:2 (0:0) | ||
| 23:30 | Club Olimpia | - | Sol de América | 2:2 (2:1) | ||
| 13/09/2022 | 00:15 | General Caballero DJLM | - | 12 de Octubre de Itauguá | 2:1 (1:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Nacional | 10 | 6 | 3 | 1 | 15:8 | 7 | 21 |
| 2 |
|
Cerro Porteño | 10 | 6 | 3 | 1 | 12:5 | 7 | 21 |
| 3 |
|
Club Olimpia | 10 | 6 | 2 | 2 | 19:11 | 8 | 20 |
| 4 |
|
Tacuary | 10 | 5 | 2 | 3 | 12:6 | 6 | 17 |
| 5 |
|
Libertad | 10 | 5 | 1 | 4 | 21:16 | 5 | 16 |
| 6 |
|
Guaireña FC | 10 | 4 | 2 | 4 | 16:14 | 2 | 14 |
| 7 |
|
Sportivo Ameliano | 10 | 4 | 1 | 5 | 12:12 | 0 | 13 |
| 8 |
|
Resistencia SC | 10 | 2 | 5 | 3 | 8:13 | -5 | 11 |
| 9 |
|
Sol de América | 10 | 3 | 2 | 5 | 9:15 | -6 | 11 |
| 10 |
|
General Caballero DJLM | 10 | 3 | 2 | 5 | 10:17 | -7 | 11 |
| 11 |
|
Guaraní | 10 | 1 | 5 | 4 | 8:13 | -5 | 8 |
| 12 |
|
12 de Octubre de Itauguá | 10 | 1 | 0 | 9 | 7:19 | -12 | 3 |
| Copa Libertadores |
