 |
 |
|
| 10/09/2019 | 21:30 | 2 de Mayo | - | Guaireña FC | 3:4 pso | |
| 23:45 | Sportivo Luqueño | - | Club Nacional | 2:0 | ||
| 11/09/2019 | 21:30 | Libertad | - | Fernando de la Mora | 3:2 | |
| 23:45 | Club Olimpia | - | Cristóbal Colón de Ñemby | 4:5 pso | ||
| 12/09/2019 | 23:45 | Ovetense FC | - | Deportivo Capiatá | 0:1 | |
| 17/09/2019 | 21:30 | Deportivo Santaní | - | River Plate | 1:0 | |
| 18/09/2019 | 23:45 | Guaraní | - | Sol de América de Santa María | 5:0 | |
| 19/09/2019 | 23:45 | Atyrá FC | - | Sol de América | 0:2 |
