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| 14/01/2025 | 17:45 | AZ Alkmaar | - | AFC Ajax | 2:0 (1:0) | |
| 19:00 | VV Noordwijk | - | BVV Barendrecht | 1:0 (0:0, 0:0) aet | ||
| 20:00 | PSV Eindhoven | - | SBV Excelsior | 5:4 (0:1, 3:3) aet | ||
| 15/01/2025 | 17:45 | Go Ahead Eagles | - | FC Twente | 3:1 (0:1) | |
| 19:00 | RKC Waalwijk | - | FC Utrecht | 1:2 (1:0) | ||
| 20:00 | Rijnsburgse Boys | - | Feyenoord | 1:4 (1:3) | ||
| 16/01/2025 | 17:45 | De Graafschap | - | Heracles Almelo | 0:2 (0:1) | |
| 20:00 | Quick Boys | - | sc Heerenveen | 3:2 (1:0, 2:2) aet |
