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| 18/08/2018 | 13:30 | FC 's-Gravenzande | - | Quick Den Haag | 3:2 (1:0) | |
| 13:30 | ASWH Ido-Ambacht | - | MASV | 5:0 (1:0) | ||
| 14:00 | VV Eemdijk | - | VC Vlissingen | 3:0 (1:0) | ||
| 16:00 | Quick'20 | - | DVS'33 | 2:6 (0:2) | ||
| 16:00 | VV Alverna | - | ODIN '59 | 0:2 (0:1) | ||
| 16:00 | HSV Hoek | - | ADO '20 | 3:0 (1:0) | ||
| 16:00 | SV Urk | - | SDO Bussum | 5:4 (1:0, 1:1, 2:2) pso | ||
| 16:00 | Harkemase Boys | - | ASV De Dijk | 2:1 (1:0) | ||
| 16:00 | Sportlust '46 | - | HBS-Craeyenhout | 1:4 (1:1) | ||
| 16:00 | ZVV Zaanlandia | - | Achilles'29 | 4:5 (0:1, 1:1, 1:1) pso | ||
| 16:00 | VV GOES | - | VV Staphorst | 0:4 (0:2) | ||
| 16:00 | OSS '20 | - | VV Noordwijk | 2:4 (2:2, 2:2, 2:4) aet | ||
| 16:00 | EVV | - | VV Brielle | 7:0 (1:0) | ||
| 16:00 | SteDoCo | - | RKSV Cluzona | 1:0 (0:0) | ||
| 19/08/2018 | 13:00 | JOS Watergraafsmeer | - | RKVV Westlandia | 1:2 (0:0, 0:0, 1:2) aet | |
| 13:30 | RKSV Bekkerveld | - | USV Hercules | 2:4 (2:1) |
