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| 1st(1st leg) | AFC Ajax | - | Roda JC Kerkrade | 5:1 (2:0) | ||
| 2nd (2nd leg) | Roda JC Kerkrade | - | AFC Ajax | 4:4 (1:3) | ||
| 1st(1st leg): 27/02/1980 | 2nd (2nd leg): 12/03/1980 | Winner: AFC Ajax | ||||
| 1st(1st leg) | AZ '67 Alkmaar | - | Sparta Rotterdam | 2:1 (1:1) | ||
| 2nd (2nd leg) | Sparta Rotterdam | - | AZ '67 Alkmaar | 1:0 (1:0) | ||
| 1st(1st leg): 27/02/1980 | 2nd (2nd leg): 18/03/1980 | Winner: Sparta Rotterdam | ||||
| 1st(1st leg) | FC Den Haag | - | PSV Eindhoven | 3:1 (1:0) | ||
| 2nd (2nd leg) | PSV Eindhoven | - | FC Den Haag | 3:0 (0:0) | ||
| 1st(1st leg): 27/02/1980 | 2nd (2nd leg): 12/03/1980 | Winner: PSV Eindhoven | ||||
| 1st(1st leg) | Feyenoord | - | PEC Zwolle | 3:0 (1:0) | ||
| 2nd (2nd leg) | PEC Zwolle | - | Feyenoord | 2:2 (2:1) | ||
| 1st(1st leg): 27/02/1980 | 2nd (2nd leg): 12/03/1980 | Winner: Feyenoord | ||||
