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| 06/08/2022 | 15:00 | Puebla FC | - | Deportivo Toluca | 4:2 (1:2) | |
| 15:00 | Cruz Azul | - | Gallos Blancos | 2:1 (2:1) | ||
| 15:00 | UANL Tigres | - | Mazatlán FC | 0:1 (0:1) | ||
| 15:00 | Atlas Guadalajara | - | Santos Laguna | 1:2 (0:1) | ||
| 15:00 | Club León | - | Atlético San Luis | 1:5 (0:2) | ||
| 16:00 | FC Juárez | - | Pumas UNAM | 1:1 (0:0) | ||
| 22:00 | CF América | - | Club Necaxa | 0:0 (0:0) | ||
| 22:00 | Deportivo Guadalajara | - | CF Monterrey | 3:2 (1:0) |
| » Tables | Home | Away | First round | Second round |
| 1 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Necaxa | 6 | 3 | 3 | 0 | 15:5 | 10 | 12 |
| 2 |
|
CF América | 6 | 3 | 2 | 1 | 13:9 | 4 | 11 |
| 3 |
|
CF Pachuca | 6 | 3 | 1 | 2 | 9:9 | 0 | 10 |
| 4 |
|
Pumas UNAM | 6 | 2 | 3 | 1 | 6:7 | -1 | 9 |
| 5 |
|
Cruz Azul | 6 | 2 | 2 | 2 | 12:9 | 3 | 8 |
| 6 |
|
Deportivo Toluca | 6 | 2 | 1 | 3 | 16:15 | 1 | 7 |
| 7 |
|
Gallos Blancos | 7 | 2 | 1 | 4 | 8:15 | -7 | 7 |
| 8 |
|
FC Juárez | 7 | 1 | 3 | 3 | 6:11 | -5 | 6 |
| 9 |
|
Puebla FC | 6 | 1 | 2 | 3 | 9:14 | -5 | 5 |
| 2 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Santos Laguna | 6 | 5 | 0 | 1 | 12:7 | 5 | 15 |
| 2 |
|
Deportivo Guadalajara | 6 | 4 | 1 | 1 | 14:9 | 5 | 13 |
| 3 |
|
Mazatlán FC | 6 | 4 | 1 | 1 | 8:5 | 3 | 13 |
| 4 |
|
CF Monterrey | 7 | 4 | 0 | 3 | 14:10 | 4 | 12 |
| 5 |
|
Club Tijuana | 6 | 2 | 2 | 2 | 7:6 | 1 | 8 |
| 6 |
|
Atlético San Luis | 6 | 2 | 1 | 3 | 14:14 | 0 | 7 |
| 7 |
|
Atlas Guadalajara | 7 | 2 | 1 | 4 | 6:9 | -3 | 7 |
| 8 |
|
UANL Tigres | 6 | 2 | 0 | 4 | 7:10 | -3 | 6 |
| 9 |
|
Club León | 6 | 0 | 0 | 6 | 4:16 | -12 | 0 |
| Playoffs | |
| Playoffs |
