 |
 |
|
|
| 10/04/2021 | 01:30 | Club Necaxa | - | Pumas UNAM | 0:1 (0:0) | |
| 03:30 | FC Juárez | - | Atlético San Luis | 2:1 (1:0) | ||
| 23:00 | Atlas Guadalajara | - | Club León | 1:3 (0:1) | ||
| 11/04/2021 | 01:00 | Cruz Azul | - | Deportivo Guadalajara | 1:0 (0:0) | |
| 03:05 | UANL Tigres | - | CF América | 1:3 (0:1) | ||
| 18:00 | Deportivo Toluca | - | CF Monterrey | 1:2 (0:0) | ||
| 12/04/2021 | 01:00 | Gallos Blancos | - | Santos Laguna | 1:0 (1:0) | |
| 03:06 | Club Tijuana | - | Mazatlán FC | 2:3 (2:1) | ||
| 13/04/2021 | 03:00 | CF Pachuca | - | Puebla FC | 1:3 (0:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cruz Azul | 14 | 12 | 0 | 2 | 21:7 | 14 | 36 |
| 2 |
|
CF América | 14 | 11 | 1 | 2 | 23:10 | 13 | 34 |
| 3 |
|
CF Monterrey | 14 | 7 | 4 | 3 | 20:10 | 10 | 25 |
| 4 |
|
Puebla FC | 14 | 6 | 5 | 3 | 21:13 | 8 | 23 |
| 5 |
|
Santos Laguna | 14 | 6 | 4 | 4 | 15:11 | 4 | 22 |
| 6 |
|
Atlas Guadalajara | 14 | 6 | 3 | 5 | 15:13 | 2 | 21 |
| 7 |
|
Club León | 14 | 6 | 2 | 6 | 18:18 | 0 | 20 |
| 8 |
|
Deportivo Toluca | 14 | 5 | 4 | 5 | 22:19 | 3 | 19 |
| 9 |
|
UANL Tigres | 14 | 5 | 3 | 6 | 17:19 | -2 | 18 |
| 10 |
|
Gallos Blancos | 14 | 5 | 2 | 7 | 17:23 | -6 | 17 |
| 11 |
|
Mazatlán FC | 14 | 5 | 2 | 7 | 15:22 | -7 | 17 |
| 12 |
|
Club Tijuana | 14 | 4 | 4 | 6 | 17:18 | -1 | 16 |
| 13 |
|
Pumas UNAM | 14 | 4 | 4 | 6 | 10:11 | -1 | 16 |
| 14 |
|
Deportivo Guadalajara | 14 | 3 | 7 | 4 | 18:21 | -3 | 16 |
| 15 |
|
CF Pachuca | 14 | 3 | 5 | 6 | 13:18 | -5 | 14 |
| 16 |
|
Atlético San Luis | 14 | 3 | 3 | 8 | 16:21 | -5 | 12 |
| 17 |
|
FC Juárez | 14 | 3 | 3 | 8 | 12:26 | -14 | 12 |
| 18 |
|
Club Necaxa | 14 | 2 | 4 | 8 | 13:23 | -10 | 10 |
| Playoffs | |
| Playoffs |
