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| 1st(1st leg) | Santos Laguna | - | UANL Tigres | 1:1 (1:1) | ||
| 2nd (2nd leg) | UANL Tigres | - | Santos Laguna | 0:1 (0:0) | ||
| 1st(1st leg): 14/05/2015 01:00 | 2nd (2nd leg): 17/05/2015 01:00 | Winner: Santos Laguna | ||||
| 1st(1st leg) | CF Pachuca | - | CF América | 3:2 (3:1) | ||
| 2nd (2nd leg) | CF América | - | CF Pachuca | 3:4 (1:1) | ||
| 1st(1st leg): 14/05/2015 03:06 | 2nd (2nd leg): 16/05/2015 23:00 | Winner: CF Pachuca | ||||
| 1st(1st leg) | Gallos Blancos | - | CD Veracruz | 2:1 (1:1) | ||
| 2nd (2nd leg) | CD Veracruz | - | Gallos Blancos | 2:2 (0:1) | ||
| 1st(1st leg): 15/05/2015 01:00 | 2nd (2nd leg): 18/05/2015 02:00 | Winner: Gallos Blancos | ||||
| 1st(1st leg) | Deportivo Guadalajara | - | Atlas Guadalajara | 0:0 (0:0) | ||
| 2nd (2nd leg) | Atlas Guadalajara | - | Deportivo Guadalajara | 1:4 (1:3) | ||
| 1st(1st leg): 15/05/2015 03:00 | 2nd (2nd leg): 18/05/2015 00:00 | Winner: Deportivo Guadalajara | ||||
