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| 1st(1st leg) | UAG Tecos | - | CF Monterrey | 0:3 (0:1) | ||
| 2nd (2nd leg) | CF Monterrey | - | UAG Tecos | 4:0 (1:0) | ||
| 1st(1st leg): 01/12/2005 01:00 | 2nd (2nd leg): 03/12/2005 23:00 | Winner: CF Monterrey | ||||
| 1st(1st leg) | CF Pachuca | - | Club Necaxa | 2:0 (2:0) | ||
| 2nd (2nd leg) | Club Necaxa | - | CF Pachuca | 0:2 (0:1) | ||
| 1st(1st leg): 01/12/2005 03:00 | 2nd (2nd leg): 04/12/2005 02:30 | Winner: CF Pachuca | ||||
| 1st(1st leg) | Deportivo Toluca | - | Cruz Azul | 1:0 (0:0) | ||
| 2nd (2nd leg) | Cruz Azul | - | Deportivo Toluca | 0:0 (0:0) | ||
| 1st(1st leg): 01/12/2005 21:00 | 2nd (2nd leg): 05/12/2005 02:00 | Winner: Deportivo Toluca | ||||
| 1st(1st leg) | UANL Tigres | - | CF América | 1:3 (0:1) | ||
| 2nd (2nd leg) | CF América | - | UANL Tigres | 1:4 (0:3) | ||
| 1st(1st leg): 02/12/2005 02:45 | 2nd (2nd leg): 04/12/2005 23:00 | Winner: UANL Tigres | ||||
