23/10/2010 13:00 FC Sfîntul Gheorghe - Gagauziya Comrat 2:2 (1:2)
13:00 FC Zimbru - CSCA-Rapid Chişinău 0:0 (0:0)
13:00 FC Milsami - Dinamo Bender 1:1 (1:0)
13:00 FC Olimpia Bălți - FC Costuleni 4:1 (3:0)
13:00 Nistru Otaci - Dacia Chişinău 1:1 (0:1)
25/10/2010 13:00 FC Iskra-Stal - FC Sheriff 0:1 (0:0)
09/12/2010 13:00 FC Tiraspol - FC Academia UTM 2:1 (1:0)
# Team M. W D L goals Dif. Pt.
1 FC Olimpia Bălți, Moldova FC Olimpia Bălți 13 8 3 2 26:8 18 27
2 Dacia Chişinău, Moldova Dacia Chişinău 13 7 6 0 16:5 11 27
3 FC Sheriff, Moldova FC Sheriff 13 7 5 1 19:4 15 26
4 FC Iskra-Stal, Moldova FC Iskra-Stal 13 7 5 1 21:7 14 26
5 FC Milsami, Moldova FC Milsami 13 6 5 2 18:8 10 23
6 FC Zimbru, Moldova FC Zimbru 13 5 6 2 12:6 6 21
7 CSCA-Rapid Chişinău, Moldova CSCA-Rapid Chişinău 13 6 3 4 10:8 2 21
8 FC Academia UTM, Moldova FC Academia UTM 13 5 5 3 18:8 10 20
9 FC Tiraspol, Moldova FC Tiraspol 13 5 1 7 18:23 -5 16
10 Dinamo Bender, Moldova Dinamo Bender 13 3 2 8 8:29 -21 11
11 Gagauziya Comrat, Moldova Gagauziya Comrat 13 2 2 9 15:25 -10 8
12 Nistru Otaci, Moldova Nistru Otaci 13 2 2 9 9:20 -11 8
13 FC Costuleni, Moldova FC Costuleni 13 2 2 9 9:34 -25 8
14 FC Sfîntul Gheorghe, Moldova FC Sfîntul Gheorghe 13 1 3 9 10:24 -14 6
  Champions League Quali.
  Europa League
  Relegation