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| 1st(1st leg) | Marathón | - | Motagua | 0:0 | ||
| 2nd (2nd leg) | Motagua | - | Marathón | 0:2 | ||
| 1st(1st leg): 03/05/2012 02:30 | 2nd (2nd leg): 05/05/2012 19:00 | Winner: Marathón | ||||
| 1st(1st leg) | Real España | - | Olimpia | 0:1 | ||
| 2nd (2nd leg) | Olimpia | - | Real España | 5:0 | ||
| 1st(1st leg): 04/05/2012 02:30 | 2nd (2nd leg): 06/05/2012 23:00 | Winner: Olimpia | ||||
