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| 1st(1st leg) | Athletic Club | - | Real Valladolid | 1:1 | ||
| 2nd (2nd leg) | Real Valladolid | - | Athletic Club | 3:1 | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: Real Valladolid | ||||
| 1st(1st leg) | Cádiz CF | - | Real Betis | 0:0 | ||
| 2nd (2nd leg) | Real Betis | - | Cádiz CF | 2:4 pso | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: Cádiz CF | ||||
| 1st(1st leg) | Recreativo Huelva | - | RCD Mallorca | 0:0 | ||
| 2nd (2nd leg) | RCD Mallorca | - | Recreativo Huelva | 5:3 pso | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: RCD Mallorca | ||||
| 1st(1st leg) | RC Celta | - | CA Osasuna | 1:0 | ||
| 2nd (2nd leg) | CA Osasuna | - | RC Celta | 3:4 pso | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: RC Celta | ||||
| 1st(1st leg) | Deportivo La Coruña | - | Real Sociedad | 0:0 | ||
| 2nd (2nd leg) | Real Sociedad | - | Deportivo La Coruña | 1:3 pso | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: Deportivo La Coruña | ||||
| 1st(1st leg) | Espanyol Barcelona | - | Atlético Madrid | 0:0 | ||
| 2nd (2nd leg) | Atlético Madrid | - | Espanyol Barcelona | 3:0 | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: Atlético Madrid | ||||
| 1st(1st leg) | Racing Santander | - | FC Barcelona | 0:1 | ||
| 2nd (2nd leg) | FC Barcelona | - | Racing Santander | 3:2 | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: FC Barcelona | ||||
| 1st(1st leg) | Sporting Gijón | - | Real Madrid | 5:5 | ||
| 2nd (2nd leg) | Real Madrid | - | Sporting Gijón | 5:2 | ||
| 1st(1st leg): 16/02/1989 | 2nd (2nd leg): 22/02/1989 | Winner: Real Madrid | ||||
