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| 1st(1st leg) | AEK Larnaca | - | N&S Erimis | 5:0 (2:0) | ||
| 2nd (2nd leg) | N&S Erimis | - | AEK Larnaca | 1:8 (0:4) | ||
| 1st(1st leg): 06/01/2016 13:00 | 2nd (2nd leg): 13/01/2016 13:00 | Winner: AEK Larnaca | ||||
| 1st(1st leg) | Paphos FC | - | ASIL Lysi | 3:0 (3:0) | ||
| 2nd (2nd leg) | ASIL Lysi | - | Paphos FC | 0:2 (0:1) | ||
| 1st(1st leg): 06/01/2016 13:00 | 2nd (2nd leg): 26/01/2016 13:00 | Winner: Paphos FC | ||||
| 1st(1st leg) | Aris Limassol | - | Olympiakos Nikosia | 1:0 (1:0) | ||
| 2nd (2nd leg) | Olympiakos Nikosia | - | Aris Limassol | 1:3 (0:1) | ||
| 1st(1st leg): 06/01/2016 14:00 | 2nd (2nd leg): 13/01/2016 13:00 | Winner: Aris Limassol | ||||
| 1st(1st leg) | Omonia Nikosia | - | Ethnikos Achna | 2:0 (0:0) | ||
| 2nd (2nd leg) | Ethnikos Achna | - | Omonia Nikosia | 1:3 (1:1) | ||
| 1st(1st leg): 06/01/2016 14:00 | 2nd (2nd leg): 20/01/2016 17:00 | Winner: Omonia Nikosia | ||||
| 1st(1st leg) | Anorthosis Famagusta | - | Anagennisi Derynias | 2:1 (1:0) | ||
| 2nd (2nd leg) | Anagennisi Derynias | - | Anorthosis Famagusta | 0:0 (0:0) | ||
| 1st(1st leg): 06/01/2016 16:00 | 2nd (2nd leg): 20/01/2016 13:00 | Winner: Anorthosis Famagusta | ||||
| 1st(1st leg) | AEL Limassol | - | AO Agia Napa | 1:0 (0:0) | ||
| 2nd (2nd leg) | AO Agia Napa | - | AEL Limassol | 1:2 (0:1) | ||
| 1st(1st leg): 13/01/2016 15:00 | 2nd (2nd leg): 20/01/2016 15:00 | Winner: AEL Limassol | ||||
| 1st(1st leg) | Nea Salamina | - | APOEL Nikosia | 0:1 (0:0) | ||
| 2nd (2nd leg) | APOEL Nikosia | - | Nea Salamina | 3:2 (2:0) | ||
| 1st(1st leg): 13/01/2016 17:00 | 2nd (2nd leg): 27/01/2016 15:00 | Winner: APOEL Nikosia | ||||
| 1st(1st leg) | Apollon Limassol | - | Ermis Aradippou | 3:1 (1:0) | ||
| 2nd (2nd leg) | Ermis Aradippou | - | Apollon Limassol | 0:1 (0:0) | ||
| 1st(1st leg): 20/01/2016 14:00 | 2nd (2nd leg): 27/01/2016 17:00 | Winner: Apollon Limassol | ||||
