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| 1st(1st leg) | CS Herediano | - | Limón FC | 2:0 (0:0) | ||
| 2nd (2nd leg) | Limón FC | - | CS Herediano | 2:2 (1:1) | ||
| 1st(1st leg): 10/04/2011 03:00 | 2nd (2nd leg): 17/04/2011 21:00 | Winner: CS Herediano | ||||
| 1st(1st leg) | CS Cartaginés | - | AD San Carlos | 1:1 (0:1) | ||
| 2nd (2nd leg) | AD San Carlos | - | CS Cartaginés | 4:1 (1:0) | ||
| 1st(1st leg): 10/04/2011 18:00 | 2nd (2nd leg): 17/04/2011 22:00 | Winner: AD San Carlos | ||||
| 1st(1st leg) | Santos de Guápiles | - | Deportivo Saprissa | 1:2 (1:1) | ||
| 2nd (2nd leg) | Deportivo Saprissa | - | Santos de Guápiles | 1:1 (0:1) | ||
| 1st(1st leg): 10/04/2011 22:00 | 2nd (2nd leg): 18/04/2011 00:00 | Winner: Deportivo Saprissa | ||||
| 1st(1st leg) | Municipal Pérez Zeledón | - | LD Alajuelense | 1:1 (0:0) | ||
| 2nd (2nd leg) | LD Alajuelense | - | Municipal Pérez Zeledón | 1:0 (1:0) | ||
| 1st(1st leg): 10/04/2011 23:00 | 2nd (2nd leg): 17/04/2011 23:30 | Winner: LD Alajuelense | ||||
