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| 1st(1st leg) | São Paulo FC | - | Atlético Nacional | 0:2 (0:0) | ||
| 2nd (2nd leg) | Atlético Nacional | - | São Paulo FC | 2:1 (1:1) | ||
| 1st(1st leg): 07/07/2016 01:45 | 2nd (2nd leg): 14/07/2016 01:45 | Winner: Atlético Nacional | ||||
| 1st(1st leg) | Independiente del Valle | - | Boca Juniors | 2:1 (0:1) | ||
| 2nd (2nd leg) | Boca Juniors | - | Independiente del Valle | 2:3 (1:1) | ||
| 1st(1st leg): 08/07/2016 01:45 | 2nd (2nd leg): 15/07/2016 01:45 | Winner: Independiente del Valle | ||||
