 |
 |
|
|
| 06/09/2021 | 15:00 | Cobresal | - | Ñublense | 4:1 (2:0) | |
| 07/09/2021 | 00:00 | Universidad de Chile | - | La Serena | 1:1 (0:1) | |
| 19:00 | Melipilla | - | Unión Española | 0:3 (0:2) | ||
| 21:30 | Antofagasta | - | Curicó Unido | 1:1 (1:1) | ||
| 08/09/2021 | 00:00 | Universidad Católica | - | Audax Italiano | 3:1 (1:0) | |
| 19:30 | Unión La Calera | - | Santiago Wanderers | 0:1 (0:1) | ||
| 22:00 | O'Higgins | - | Colo-Colo | 2:3 (1:0) | ||
| 09/09/2021 | 00:30 | Everton | - | Palestino | 1:0 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colo-Colo | 19 | 11 | 4 | 4 | 30:17 | 13 | 37 |
| 2 |
|
Audax Italiano | 19 | 9 | 7 | 3 | 22:16 | 6 | 34 |
| 3 |
|
Universidad Católica | 19 | 10 | 2 | 7 | 31:25 | 6 | 32 |
| 4 |
|
Unión La Calera | 19 | 9 | 5 | 5 | 20:20 | 0 | 32 |
| 5 |
|
Universidad de Chile | 18 | 8 | 6 | 4 | 23:16 | 7 | 30 |
| 6 |
|
Unión Española | 19 | 9 | 3 | 7 | 30:25 | 5 | 30 |
| 7 |
|
Cobresal | 19 | 8 | 5 | 6 | 25:19 | 6 | 29 |
| 8 |
|
Antofagasta | 19 | 7 | 7 | 5 | 24:22 | 2 | 28 |
| 9 |
|
Everton | 19 | 7 | 6 | 6 | 17:17 | 0 | 27 |
| 10 |
|
Ñublense | 19 | 6 | 7 | 6 | 28:24 | 4 | 25 |
| 11 |
|
La Serena | 19 | 5 | 7 | 7 | 25:24 | 1 | 22 |
| 12 |
|
O'Higgins | 19 | 5 | 7 | 7 | 16:24 | -8 | 22 |
| 13 |
|
Huachipato | 18 | 4 | 9 | 5 | 22:23 | -1 | 21 |
| 14 |
|
Palestino | 19 | 6 | 3 | 10 | 25:29 | -4 | 21 |
| 15 |
|
Melipilla | 19 | 5 | 5 | 9 | 23:32 | -9 | 20 |
| 16 |
|
Curicó Unido | 19 | 4 | 7 | 8 | 21:26 | -5 | 19 |
| 17 |
|
Santiago Wanderers | 18 | 1 | 2 | 15 | 10:33 | -23 | 5 |
| Copa Libertadores | |
| Qualification | |
| Copa Sudamericana | |
| Playoffs | |
| Relegation |
