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| 15/09/2021 | 20:00 | Atlético Madrid | - | FC Porto | 0:0 (0:0) | |
| 20:00 | Liverpool FC | - | AC Milan | 3:2 (1:2) | ||
| 28/09/2021 | 20:00 | FC Porto | - | Liverpool FC | 1:5 (0:2) | |
| 20:00 | AC Milan | - | Atlético Madrid | 1:2 (1:0) | ||
| 19/10/2021 | 20:00 | Atlético Madrid | - | Liverpool FC | 2:3 (2:2) | |
| 20:00 | FC Porto | - | AC Milan | 1:0 (0:0) | ||
| 03/11/2021 | 17:45 | AC Milan | - | FC Porto | 1:1 (0:1) | |
| 20:00 | Liverpool FC | - | Atlético Madrid | 2:0 (2:0) | ||
| 24/11/2021 | 20:00 | Liverpool FC | - | FC Porto | 2:0 (0:0) | |
| 20:00 | Atlético Madrid | - | AC Milan | 0:1 (0:0) | ||
| 07/12/2021 | 20:00 | FC Porto | - | Atlético Madrid | 1:3 (0:0) | |
| 20:00 | AC Milan | - | Liverpool FC | 1:2 (1:1) |
| » Tables | Home | Away | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Liverpool FC | 6 | 6 | 0 | 0 | 17:6 | 11 | 18 |
| 2 |
|
Atlético Madrid | 6 | 2 | 1 | 3 | 7:8 | -1 | 7 |
| 3 |
|
FC Porto | 6 | 1 | 2 | 3 | 4:11 | -7 | 5 |
| 4 |
|
AC Milan | 6 | 1 | 1 | 4 | 6:9 | -3 | 4 |
| Next Round | |
| Europa League |
