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| 1st(1st leg) | Manchester City | - | Borussia Dortmund | 2:1 (1:0) | ||
| 2nd (2nd leg) | Borussia Dortmund | - | Manchester City | 1:2 (1:0) | ||
| 1st(1st leg): 06/04/2021 20:00 | 2nd (2nd leg): 14/04/2021 20:00 | Winner: Manchester City | ||||
| 1st(1st leg) | Real Madrid | - | Liverpool FC | 3:1 (2:0) | ||
| 2nd (2nd leg) | Liverpool FC | - | Real Madrid | 0:0 (0:0) | ||
| 1st(1st leg): 06/04/2021 20:00 | 2nd (2nd leg): 14/04/2021 20:00 | Winner: Real Madrid | ||||
| 1st(1st leg) | FC Porto | - | Chelsea FC | 0:2 (0:1) | ||
| 2nd (2nd leg) | Chelsea FC | - | FC Porto | 0:1 (0:0) | ||
| 1st(1st leg): 07/04/2021 20:00 | 2nd (2nd leg): 13/04/2021 20:00 | Winner: Chelsea FC | ||||
| 1st(1st leg) | Bayern München | - | Paris Saint-Germain | 2:3 (1:2) | ||
| 2nd (2nd leg) | Paris Saint-Germain | - | Bayern München | 0:1 (0:1) | ||
| 1st(1st leg): 07/04/2021 20:00 | 2nd (2nd leg): 13/04/2021 20:00 | Winner: Paris Saint-Germain | ||||
