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| 1st(1st leg) | Liverpool FC | - | FC Porto | 2:0 (2:0) | ||
| 2nd (2nd leg) | FC Porto | - | Liverpool FC | 1:4 (0:1) | ||
| 1st(1st leg): 09/04/2019 20:00 | 2nd (2nd leg): 17/04/2019 20:00 | Winner: Liverpool FC | ||||
| 1st(1st leg) | Tottenham Hotspur | - | Manchester City | 1:0 (0:0) | ||
| 2nd (2nd leg) | Manchester City | - | Tottenham Hotspur | 4:3 (3:2) | ||
| 1st(1st leg): 09/04/2019 20:00 | 2nd (2nd leg): 17/04/2019 20:00 | Winner: Tottenham Hotspur | ||||
| 1st(1st leg) | AFC Ajax | - | Juventus | 1:1 (0:1) | ||
| 2nd (2nd leg) | Juventus | - | AFC Ajax | 1:2 (1:1) | ||
| 1st(1st leg): 10/04/2019 20:00 | 2nd (2nd leg): 16/04/2019 20:00 | Winner: AFC Ajax | ||||
| 1st(1st leg) | Manchester United | - | FC Barcelona | 0:1 (0:1) | ||
| 2nd (2nd leg) | FC Barcelona | - | Manchester United | 3:0 (2:0) | ||
| 1st(1st leg): 10/04/2019 20:00 | 2nd (2nd leg): 16/04/2019 20:00 | Winner: FC Barcelona | ||||
