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| 1st(1st leg) | AS Roma | - | Manchester United | 0:2 (0:1) | ||
| 2nd (2nd leg) | Manchester United | - | AS Roma | 1:0 (0:0) | ||
| 1st(1st leg): 01/04/2008 19:45 | 2nd (2nd leg): 09/04/2008 19:45 | Winner: Manchester United | ||||
| 1st(1st leg) | FC Schalke 04 | - | FC Barcelona | 0:1 (0:1) | ||
| 2nd (2nd leg) | FC Barcelona | - | FC Schalke 04 | 1:0 (1:0) | ||
| 1st(1st leg): 01/04/2008 19:45 | 2nd (2nd leg): 09/04/2008 19:45 | Winner: FC Barcelona | ||||
| 1st(1st leg) | Arsenal FC | - | Liverpool FC | 1:1 (1:1) | ||
| 2nd (2nd leg) | Liverpool FC | - | Arsenal FC | 4:2 (1:1) | ||
| 1st(1st leg): 02/04/2008 19:45 | 2nd (2nd leg): 08/04/2008 19:45 | Winner: Liverpool FC | ||||
| 1st(1st leg) | Fenerbahçe | - | Chelsea FC | 2:1 (0:1) | ||
| 2nd (2nd leg) | Chelsea FC | - | Fenerbahçe | 2:0 (1:0) | ||
| 1st(1st leg): 02/04/2008 19:45 | 2nd (2nd leg): 08/04/2008 19:45 | Winner: Chelsea FC | ||||
