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|
| 1st(1st leg) | Motagua | - | CF Pachuca | 0:0 | ||
| 2nd (2nd leg) | CF Pachuca | - | Motagua | 1:0 | ||
| 1st(1st leg): 12/03/2008 00:15 | 2nd (2nd leg): 20/03/2008 03:00 | Winner: CF Pachuca | ||||
| 1st(1st leg) | Harbour View | - | D.C. United | 1:1 | ||
| 2nd (2nd leg) | D.C. United | - | Harbour View | 5:0 | ||
| 1st(1st leg): 13/03/2008 00:10 | 2nd (2nd leg): 18/03/2008 23:30 | Winner: D.C. United | ||||
| 1st(1st leg) | CSD Municipal | - | Houston Dynamo | 0:0 | ||
| 2nd (2nd leg) | Houston Dynamo | - | CSD Municipal | 3:1 | ||
| 1st(1st leg): 13/03/2008 02:10 | 2nd (2nd leg): 20/03/2008 00:30 | Winner: Houston Dynamo | ||||
| 1st(1st leg) | Atlante | - | Deportivo Saprissa | 2:1 | ||
| 2nd (2nd leg) | Deportivo Saprissa | - | Atlante | 3:0 | ||
| 1st(1st leg): 14/03/2008 03:05 | 2nd (2nd leg): 21/03/2008 02:00 | Winner: Deportivo Saprissa | ||||
