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| 1st(1st leg) | Internacional | - | Flamengo RJ | 1:1 (1:0) | ||
| 2nd (2nd leg) | Flamengo RJ | - | Internacional | 1:0 (1:0) | ||
| 1st(1st leg): 13/08/2022 15:00 | 2nd (2nd leg): 17/08/2022 19:15 | Winner: Flamengo RJ | ||||
| 1st(1st leg) | São Paulo FC | - | Athletico Paranaense | 3:1 (1:0) | ||
| 2nd (2nd leg) | Athletico Paranaense | - | São Paulo FC | 4:1 (1:1) | ||
| 1st(1st leg): 13/08/2022 18:00 | 2nd (2nd leg): 19/08/2022 19:30 | Winner: Athletico Paranaense | ||||
| 1st(1st leg) | Vasco da Gama | - | Palmeiras | 1:0 (0:0) | ||
| 2nd (2nd leg) | Palmeiras | - | Vasco da Gama | 4:3 (1:0, 1:0, 1:0) pso | ||
| 1st(1st leg): 14/08/2022 20:00 | 2nd (2nd leg): 18/08/2022 19:00 | Winner: Palmeiras | ||||
| 1st(1st leg) | América - MG | - | Corinthians SP | 0:2 (0:1) | ||
| 2nd (2nd leg) | Corinthians SP | - | América - MG | 4:2 (0:1, 0:2, 0:2) pso | ||
| 1st(1st leg): 15/08/2022 20:30 | 2nd (2nd leg): 21/08/2022 20:00 | Winner: Corinthians SP | ||||
