 |
 |
|
| 10/12/2021 | 22:15 | Platense | - | Vélez Sarsfield | 3:2 (0:0) | |
| 11/12/2021 | 00:30 | Estudiantes | - | Aldosivi | 2:3 (0:1) | |
| 20:00 | Argentinos Juniors | - | Sarmiento de Junín | 2:0 (0:0) | ||
| 20:00 | Patronato de Paraná | - | Gimnasia de La Plata | 0:0 (0:0) | ||
| 20:00 | Racing Club | - | Godoy Cruz | 2:1 (1:1) | ||
| 20:00 | Rosario Central | - | Huracán | 1:4 (0:2) | ||
| 20:00 | Unión de Santa Fe | - | Colón de Santa Fe | 3:0 (2:0) | ||
| 22:15 | Atlético Tucumán | - | River Plate | 1:1 (1:0) | ||
| 12/12/2021 | 01:00 | Boca Juniors | - | Central Córdoba SdE | 8:1 (4:0) | |
| 20:00 | San Lorenzo | - | Newell's Old Boys | 3:2 (2:2) | ||
| 22:15 | Defensa y Justicia | - | Lanús | 2:1 (1:1) | ||
| 13/12/2021 | 00:30 | Talleres de Córdoba | - | Independiente | 1:2 (0:1) | |
| 23:00 | Banfield | - | Arsenal de Sarandí | 0:0 (0:0) |
| » Tables | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
River Plate | 25 | 16 | 6 | 3 | 53:19 | 34 | 54 |
| 2 |
|
Defensa y Justicia | 25 | 13 | 8 | 4 | 43:24 | 19 | 47 |
| 3 |
|
Talleres de Córdoba | 25 | 14 | 4 | 7 | 38:28 | 10 | 46 |
| 4 |
|
Boca Juniors | 25 | 11 | 8 | 6 | 35:19 | 16 | 41 |
| 5 |
|
Vélez Sarsfield | 25 | 10 | 9 | 6 | 34:21 | 13 | 39 |
| 6 |
|
Estudiantes | 25 | 10 | 9 | 6 | 43:31 | 12 | 39 |
| 7 |
|
Colón de Santa Fe | 25 | 11 | 6 | 8 | 26:31 | -5 | 39 |
| 8 |
|
Huracán | 25 | 10 | 8 | 7 | 28:25 | 3 | 38 |
| 9 |
|
Independiente | 25 | 10 | 8 | 7 | 27:24 | 3 | 38 |
| 10 |
|
Lanús | 25 | 10 | 7 | 8 | 44:43 | 1 | 37 |
| 11 |
|
Gimnasia de La Plata | 25 | 9 | 9 | 7 | 27:28 | -1 | 36 |
| 12 |
|
Unión de Santa Fe | 25 | 10 | 4 | 11 | 32:32 | 0 | 34 |
| 13 |
|
Aldosivi | 25 | 10 | 3 | 12 | 29:39 | -10 | 33 |
| 14 |
|
Argentinos Juniors | 25 | 8 | 8 | 9 | 26:25 | 1 | 32 |
| 15 |
|
Racing Club | 25 | 8 | 8 | 9 | 24:23 | 1 | 32 |
| 16 |
|
Rosario Central | 25 | 9 | 5 | 11 | 39:41 | -2 | 32 |
| 17 |
|
Godoy Cruz | 25 | 8 | 7 | 10 | 35:33 | 2 | 31 |
| 18 |
|
Platense | 25 | 7 | 10 | 8 | 36:36 | 0 | 31 |
| 19 |
|
Newell's Old Boys | 25 | 7 | 7 | 11 | 24:32 | -8 | 28 |
| 20 |
|
Banfield | 25 | 5 | 12 | 8 | 20:25 | -5 | 27 |
| 21 |
|
San Lorenzo | 25 | 7 | 6 | 12 | 23:33 | -10 | 27 |
| 22 |
|
Central Córdoba SdE | 25 | 6 | 8 | 11 | 30:36 | -6 | 26 |
| 23 |
|
Patronato de Paraná | 25 | 5 | 10 | 10 | 23:35 | -12 | 25 |
| 24 |
|
Sarmiento de Junín | 25 | 6 | 6 | 13 | 23:33 | -10 | 24 |
| 25 |
|
Atlético Tucumán | 25 | 5 | 7 | 13 | 22:46 | -24 | 22 |
| 26 |
|
Arsenal de Sarandí | 25 | 4 | 9 | 12 | 12:34 | -22 | 21 |
| Copa Libertadores | |
| Copa Sudamericana | |
| Copa Libertadores | |
| Copa Libertadores | |
| Copa Sudamericana | |
| Copa Sudamericana | |
| Copa Sudamericana |
