| 5. Round | 03/09/2022 | Liverpool FC U21 | - | Manchester United U21 | 2:2 |  |
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| 12. Round | 29/10/2022 | Tottenham Hotspur U21 | - | Manchester United U21 | 1:1 | ||||
| 13. Round | 05/11/2022 | Manchester United U21 | - | Manchester City U21 | 1:6 | |
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| 14. Round | 06/01/2023 | Fulham FC U21 | - | Manchester United U21 | 1:2 | |
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| 15. Round | 14/01/2023 | Manchester United U21 | - | Liverpool FC U21 | 2:1 | ||||
| 17. Round | 27/01/2023 | Manchester United U21 | - | Blackburn Rovers U21 | 2:1 | ||||
| 19. Round | 20/02/2023 | Crystal Palace U21 | - | Manchester United U21 | 0:0 | |
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| 21. Round | 06/03/2023 | Manchester United U21 | - | Chelsea FC U21 | 1:3 | ||||
| 22. Round | 19/03/2023 | Manchester City U21 | - | Manchester United U21 | 6:0 | |
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| 6. Round | 05/05/2023 | Manchester United U21 | - | Leicester City U21 | 2:2 |
England