| 17. Round | 15/12/2021 | Crystal Palace | - | Southampton FC | 2:2 | ||||
| 29. Round | 13/03/2022 | Southampton FC | - | Watford FC | 1:2 | ||||
| 32. Round | 09/04/2022 | Southampton FC | - | Chelsea FC | 0:6 | ||||
| 38. Round | 22/05/2022 | Leicester City | - | Southampton FC | 4:1 |
| 17. Round | 15/12/2021 | Crystal Palace | - | Southampton FC | 2:2 | ||||
| 29. Round | 13/03/2022 | Southampton FC | - | Watford FC | 1:2 | ||||
| 32. Round | 09/04/2022 | Southampton FC | - | Chelsea FC | 0:6 | ||||
| 38. Round | 22/05/2022 | Leicester City | - | Southampton FC | 4:1 |
| William Anthony Patrick Smallbone | |
| Born: | 21.02.2000 |
| Place of birth: |
Basingstoke, 
England |
| Nationality: |
Ireland
England |
| Height: | 183 cm |
| Weight: | 61 kg |
| Position(s): | Central Midfielder Offensive Midfielder |
| Foot: | right |