| Group C | 20/09/2018 | Slavia Praha | - | Girondins Bordeaux | 1:0 | ||||
| Group C | 04/10/2018 | Zenit St. Petersburg | - | Slavia Praha | 1:0 | ||||
| Group C | 25/10/2018 | FC København | - | Slavia Praha | 0:1 |  |
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| Group C | 29/11/2018 | Girondins Bordeaux | - | Slavia Praha | 2:0 | ||||
| Group C | 13/12/2018 | Slavia Praha | - | Zenit St. Petersburg | 2:0 | ||||
| Round of 32 | 14/02/2019 | Slavia Praha | - | KRC Genk | 0:0 | ||||
| Round of 32 | 21/02/2019 | KRC Genk | - | Slavia Praha | 1:4 |  |
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| Round of 16 | 07/03/2019 | Sevilla FC | - | Slavia Praha | 2:2 | |
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| Quarter-finals | 11/04/2019 | Slavia Praha | - | Chelsea FC | 0:1 | |
Czech Republic
