| 1. Round | 21/08/2021 | Cape Town City FC | - | SuperSport United | 0:0 | ||||
| 2. Round | 25/08/2021 | SuperSport United | - | Golden Arrows | 3:1 |  |
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| 5. Round | 25/09/2021 | SuperSport United | - | Maritzburg United | 2:1 | ||||
| 6. Round | 02/10/2021 | Chippa United | - | SuperSport United | 0:0 | ||||
| 7. Round | 16/10/2021 | SuperSport United | - | Baroka FC | 2:0 | ||||
| 8. Round | 24/10/2021 | SuperSport United | - | Kaizer Chiefs | 1:2 | ||||
| 10. Round | 05/11/2021 | SuperSport United | - | TS Galaxy | 2:1 | |
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| 11. Round | 20/11/2021 | SuperSport United | - | Marumo Gallants | 1:2 | ||||
| 19. Round | 24/11/2021 | Mamelodi Sundowns | - | SuperSport United | 2:2 | ||||
| 21. Round | 05/03/2022 | SuperSport United | - | AmaZulu FC | 2:0 |
South Africa