| 1. Round | 29/08/2021 | SV Schermbeck | - | Westfalia Herne | 6:0 | ||||
| 2. Round | 03/09/2021 | Westfalia Herne | - | SG Wattenscheid 09 | 1:3 | ||||
| 3. Round | 12/09/2021 | FCE Rheine | - | Westfalia Herne | 1:0 | ||||
| 15. Round | 05/12/2021 | Westfalia Herne | - | Westfalia Rhynern | 2:0 | ||||
| 16. Round | 12/12/2021 | Holzwickeder SC | - | Westfalia Herne | 1:1 | ||||
| 17. Round | 27/02/2022 | Westfalia Herne | - | ASC 09 Dortmund | 2:4 | ||||
| 18. Round | 06/03/2022 | SG Finnentrop/Bamenohl | - | Westfalia Herne | 4:0 | ||||
| 19. Round | 13/03/2022 | Westfalia Herne | - | 1. FC Kaan-Marienborn | 2:5 | ||||
| 20. Round | 03/04/2022 | Viktoria Clarholz | - | Westfalia Herne | 2:0 |  |
Jamaica
USA