| Div. Prof. | 05/08/21 | The Strongest | - | Real Tomayapo | 2:0 |  |
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| Div. Prof. | 18/08/21 | The Strongest | - | Nacional Potosí | 7:0 | |
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| Div. Prof. | 27/09/21 | The Strongest | - | Always Ready | 1:1 | |
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| Div. Prof. | 23/10/21 | The Strongest | - | Real Potosí | 1:0 | ||||
| Div. Prof. | 05/12/21 | The Strongest | - | Club San José | 2:0 | ||||
| Div. Prof. | 12/12/21 | Real Santa Cruz | - | The Strongest | 1:0 |
Panama