| 9. Round | 09/10/2021 | US Granvillaise | - | US Saint-Malo | 1:0 | ||||
| 10. Round | 23/10/2021 | US Saint-Malo | - | SO Romorantin | 0:2 | ||||
| 11. Round | 07/11/2021 | FC Rouen 1899 | - | US Saint-Malo | 0:1 | ||||
| 13. Round | 04/12/2021 | FC Versailles | - | US Saint-Malo | 1:0 |  |
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| 14. Round | 11/12/2021 | SM Caen (CFA) | - | US Saint-Malo | 0:0 | ||||
| 15. Round | 29/01/2022 | US Saint-Malo | - | Stade Plabennec | 1:1 | ||||
| 27. Round | 30/04/2022 | US Saint-Malo | - | FC Versailles | 1:2 |  |
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France