| 1. Round | 30/08/1980 | Chemie Schönebeck | - | SG Dynamo Eisleben | 0:5 | ||||
| 2. Round | 06/09/1980 | SG Dynamo Eisleben | - | BSG Stahl Nordwest Leipzig | 1:1 | ||||
| 3. Round | 13/09/1980 | ASG Vorwärts Dessau | - | SG Dynamo Eisleben | 0:1 | ||||
| 4. Round | 20/09/1980 | BSG Chemie Leipzig | - | SG Dynamo Eisleben | 2:2 | ||||
| 5. Round | 04/10/1980 | BSG Stahl Thale | - | SG Dynamo Eisleben | 3:1 | ||||
| 6. Round | 07/10/1980 | BSG Chemie Wolfen | - | SG Dynamo Eisleben | 1:1 | ||||
| 7. Round | 19/10/1980 | SG Dynamo Eisleben | - | BSG Chemie Buna Schkopau | 6:1 | ||||
| 18. Round | 21/03/1981 | BSG Chemie Buna Schkopau | - | SG Dynamo Eisleben | 1:1 | ||||
| 19. Round | 28/03/1981 | SG Dynamo Eisleben | - | BSG Lokomotive Stendal | 1:1 | ||||
| 20. Round | 03/04/1981 | BSG Chemie Zeitz | - | SG Dynamo Eisleben | 1:0 | ||||
| 21. Round | 11/04/1981 | SG Dynamo Eisleben | - | BSG Stahl Blankenburg | 2:1 | ||||
| 22. Round | 16/04/1981 | BSG MK Sangerhausen | - | SG Dynamo Eisleben | 0:2 |
Germany