| 1. Round | 19/08/2020 | Alebrijes de Oaxaca | - | Leones Negros | 1:0 | ||||
| 2. Round | 30/08/2020 | Leones Negros | - | Mineros de Zacatecas | 1:1 |  |
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| 3. Round | 06/09/2020 | Atlante | - | Leones Negros | 0:1 | ||||
| 4. Round | 11/09/2020 | Leones Negros | - | TM Fútbol Club | 1:2 | ||||
| 5. Round | 15/09/2020 | Coyotes de Tlaxcala | - | Leones Negros | 1:3 | ||||
| 11. Round | 22/10/2020 | Leones Negros | - | Cancún FC | 0:1 | ||||
| 12. Round | 29/10/2020 | Leones Negros | - | Atlético Morelia | 0:0 | |
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| 8. Round | 01/11/2020 | Venados FC | - | Leones Negros | 2:1 |
Mexico