| 14. Round | 19/12/2020 | Newcastle United | - | Fulham FC | 1:1 | ||||
| 18. Round | 12/01/2021 | Sheffield United | - | Newcastle United | 1:0 | ||||
| 23. Round | 06/02/2021 | Newcastle United | - | Southampton FC | 3:2 | ||||
| 27. Round | 07/03/2021 | West Bromwich Albion | - | Newcastle United | 0:0 | ||||
| 28. Round | 12/03/2021 | Newcastle United | - | Aston Villa | 1:1 | ||||
| 29. Round | 20/03/2021 | Brighton & Hove Albion | - | Newcastle United | 3:0 |  |
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| 30. Round | 04/04/2021 | Newcastle United | - | Tottenham Hotspur | 2:2 | |
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| 31. Round | 11/04/2021 | Burnley FC | - | Newcastle United | 1:2 | ||||
| 32. Round | 17/04/2021 | Newcastle United | - | West Ham United | 3:2 | ||||
| 33. Round | 24/04/2021 | Liverpool FC | - | Newcastle United | 1:1 | ||||
| 34. Round | 02/05/2021 | Newcastle United | - | Arsenal FC | 0:2 | ||||
| 35. Round | 07/05/2021 | Leicester City | - | Newcastle United | 2:4 |  |
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| 36. Round | 14/05/2021 | Newcastle United | - | Manchester City | 3:4 | ||||
| 37. Round | 19/05/2021 | Newcastle United | - | Sheffield United | 1:0 | ||||
| 38. Round | 23/05/2021 | Fulham FC | - | Newcastle United | 0:2 |
England