| 7. Round | 11/09/2021 | Charlton Athletic | - | Cheltenham Town | 1:2 | ||||
| 8. Round | 18/09/2021 | Wycombe Wanderers | - | Charlton Athletic | 2:1 |  |
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| 9. Round | 25/09/2021 | Charlton Athletic | - | Portsmouth FC | 2:2 | |
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| 11. Round | 02/10/2021 | Fleetwood Town | - | Charlton Athletic | 1:2 | ||||
| 13. Round | 16/10/2021 | Lincoln City | - | Charlton Athletic | 2:1 | ||||
| 14. Round | 19/10/2021 | Charlton Athletic | - | Accrington Stanley | 2:3 | |
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| 20. Round | 27/11/2021 | Shrewsbury Town | - | Charlton Athletic | 1:0 | |
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| 22. Round | 11/12/2021 | Charlton Athletic | - | Cambridge United | 2:0 | ||||
| 23. Round | 18/12/2021 | Plymouth Argyle | - | Charlton Athletic | 1:0 |
Senegal
