| 5. Round | 25/08/2005 | Club San Luis | - | Atlante | 2:2 | ||||
| 7. Round | 11/09/2005 | Club San Luis | - | Dorados de Sinaloa | 4:1 | ||||
| 8. Round | 18/09/2005 | Santos Laguna | - | Club San Luis | 3:1 | ||||
| 9. Round | 25/09/2005 | Club San Luis | - | Deportivo Guadalajara | 1:2 | ||||
| 11. Round | 02/10/2005 | CF América | - | Club San Luis | 3:1 | ||||
| 12. Round | 16/10/2005 | Club San Luis | - | Veracruz (old) | 1:0 | ||||
| 13. Round | 22/10/2005 | Cruz Azul | - | Club San Luis | 3:0 |  |
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| 14. Round | 30/10/2005 | Club San Luis | - | CF Monterrey | 1:2 | ||||
| 15. Round | 06/11/2005 | CF Pachuca | - | Club San Luis | 0:0 |
Mexico