| 5. Round | 11/09/2022 | Hertha Zehlendorf | - | FC Mecklenburg Schwerin | 4:1 | ||||
| 7. Round | 02/10/2022 | TSG Neustrelitz | - | FC Mecklenburg Schwerin | 4:1 |  |
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| 8. Round | 08/10/2022 | FC Mecklenburg Schwerin | - | Eintracht Mahlsdorf | 1:2 | ||||
| 13. Round | 12/11/2022 | FC Mecklenburg Schwerin | - | RSV Eintracht 1949 | 2:1 | ||||
| 14. Round | 25/11/2022 | Dynamo Schwerin | - | FC Mecklenburg Schwerin | 4:1 | ||||
| 16. Round | 10/12/2022 | Optik Rathenow | - | FC Mecklenburg Schwerin | 2:1 | |
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| 19. Round | 05/02/2023 | 1. FC Frankfurt (Oder) | - | FC Mecklenburg Schwerin | 1:5 | ||||
| 22. Round | 25/02/2023 | FC Mecklenburg Schwerin | - | Hertha Zehlendorf | 2:2 |
Germany
Spain